Publications
For access to selected works, see the Miller Conrad ScholarWorks page.
For licensing opportunities, see the 菠菜网lol正规平台 IP Licensing page [pdf].
(菠菜网lol正规平台 student co-authors are underlined)
16. Miller Conrad, L. C.*; Perez, L. P.*, “A geneticist transcribing the chemical language of bacteria,” Isr. J. Chem. 2023, 63, e202200079. (Invited review in honor of Bonnie Bassler being awarded the Wolf Prize; *joint corresponding authors)
15. Miller Conrad, L. C.; Tran, M. L. N.; “Antibiotic adjuvants for gram negative bacteria,” U.S. Patent Application No. PCT/US2023/068038, Filing date: June 13, 2023.
14. Miller Conrad, L. C.; Semmelhack, M. F.; Zhang, Z.; Tran, M. L. N.; Blankenship, L. R., “Antibacterial adjuvants and applications thereof,” International Patent Application No. WO 2022/036208, Filing date: Aug. 13, 2021; Publication Date Feb. 17, 2022. See 菠菜网lol正规平台's Technology Transfer website [pdf].
13. Zhang, Z.; Ortega, D.; Rush, A.; Blankenship, L. R.; Cheng, Z. J.; Moore, R. E.; Tran, M. L. N.; Sandoval, L. G.; Aboulhosn, K.; Watanabe, S.; Cortez, K. S.; Perlman, D.; Semmelhack, M. F.; Miller Conrad, L. C., “Antibiotic adjuvant activity revealed in a photoaffinity approach to determine the molecular target of antipyocyanin compounds,” ACS Infect. Dis. 2021, 7, 535-543.
12. Sass, G; Miller Conrad, L. C.; Nguyen, T.-T. H.; Stevens, D. A.,“The Pseudomonas aeruginosa product pyochelin interferes with Trypanosoma cruzi infection and multiplication in vitro,” Trans. R. Soc. Trop. Med. Hyg., 2020, 114, 492-498.
11. Chaparian, R. R.; Tran, M. L. N., Miller Conrad, L. C.; Rusch, D. B.; van Kessel, J. C., “Global H-NS counter-silencing by LuxR activates quorum sensing gene expression,” Nucleic Acids Res., 2020, 48, 171-183.
10. Tran, A.; Tang, A.; O’Loughlin, C. T. O.; Balistreri, A.†; Chang, E.†; Coto Villa, D.†; Li, J.†; Varshney, A.†; Jimenez, V.; Pyle, J.; Tsujimoto, B.; Wellbrook, C.; Vargas, C.; Duong, A.; Ali, N.; Matthews, S. Y.; Levinson, S.; Woldemariam, S; Khuri, S.; Bremer, M.; Eggers, D. K.; L’Etoile, N.; Miller Conrad, L. C.*, VanHoven, M. K.,* "C. elegans avoids toxin-producing Streptomyces using a seven transmembrane domain chemosensory receptor." eLife, 2017, 6, e23770. († authors contributed equally; * joint corresponding authors)
9. Bassler, B. L.; Semmelhack, M. F.; Drescher, K.; Siryaporn, A.; Miller, L. C.; O’Loughlin, C. T.,“Molecules and compositions that inhibit gram negative bacteria and their uses,” U.S. Patent 9,751,851 B2; Filing date: Sept. 19, 2014. Date of Patent: Sept. 5, 2017.
8. Bassler, B. L.; Stone, H. A.; Semmelhack, M. F.; Drescher, K.; Shen, Y.; O’Loughlin, C. T.; Miller, L. C., “Systems and methods to detect biofilm streamer growth and their uses,” U.S. Patent Appl. No. 14/589,845; Filing date: Jan. 1, 2015; Publication date: July 9, 2015.
7. Miller, L. C.; O’Loughlin, C. T.; Zhang, Z.; Siryaporn, A; Silpe, J. E.; Bassler, B. L.; Semmelhack, M. F.*, “Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa.” J. Med. Chem., 2015, 58, 1298.
6. Ke, X.; Miller, L. C.; Bassler, B. L.*,“Determinants governing ligand specificity of the Vibrio harveyi LuxN quorum-sensing receptor.” Mol. Microbiol., 2015, 95, 127.
5. Ke, X.; Miller, L. C.; Ng, W.-L.; Bassler, B. L.*, "CqsA-CqsS quorum-sensing signal-receptor specificity in Photobacterium angustum." Mol. Microbiol., 2014, 91, 821.
4. O'Loughlin, C. T.; Miller, L. C.; Drescher, K.; Siryaporn, A.; Semmelhack, M. F.; Bassler, B. L.*, "Quorum-sensing inhibitors block P. aeruginosa virulence and biofilm production." Proc. Nat. Acad. Sci., 2013, 110, 17981.
3. Miller, L. C.; Sarpong, R.* "Divergent reactions on racemic mixtures." Chem. Soc. Rev., 2011, 40, 4550.
2. Lian, Y.; Miller, L. C.; Born, S.; Sarpong, R.*; Davies, H. M. L.*, "Catalyst-controlled [4 + 3] cycloaddition applied to the total synthesis of barekoxide and barekol." J. Am. Chem. Soc., 2010, 132, 12422.
1. Miller, L. C.; Ndungu, J. M.; Sarpong, R.* "Parallel kinetic resolution approach to the cyathane and cyanthiwigin diterpenes using a cyclopropanation/Cope rearrangement." Angew. Chem. Int. Ed., 2009, 48, 2398.
